BioCyst

Sodium Hyaluronate 40mg/50ml

BioCyst is an effective treatment for interstitial cystitis. The active ingredient in BioCyst is sterile Hyaluronic acid. Hyaluronic acid is a substance found naturally in the body including the GAG layer of the bladder. This GAG layer when healthy helps protect the highly sensitive bladder wall. BioCyst replenishes the GAG layer in IC patients.

BioCyst contains sodium hyaluronate 40mg/50ml. Hyaluronic acid is the mucopolysaccharide and is one of the most prevalent bladder GAG components. There have been numerous studies showing that GAG replenishment therapies are effective in treating GAG deficient IC patients. It is felt they help to re-establish bladder GAG barrier function.

 

Description of Interstitial Cystitis:

Interstitial Cystitis (IC) is an inflammatory disease of the bladder wall and its cause is not yet fully understood. Current theory suggests IC is the result of changes or leaks in the protective lining of the bladder, the Glycosaminoglycan (GAG) layer. These leaks allow chemicals, toxins and other harmful elements in urine to irritate the bladder wall.

Once established IC is a chronic disease, which can persist throughout life. IC is characterized by patients suffering pelvic/bladder pain, urgency and frequency of urination. Long-term inflammation can lead to scarring and stiffening of the bladder, decreased bladder capacity, glomerulations and in rare cases, ulcers in the bladder lining. Although the symptoms of IC may be difficult to cope with, the condition is not life threatening. Effective treatments such as BioCyst, allow many patients to manage their symptoms successfully.

 

Who does Interstitial Cystitis effect:

IC can affect people of any age, race, or sex. It is, however, most commonly found in women. IC is a disease marked by periods with flare-ups and remissions and its symptoms can be exacerbated by menstruation, urinary tract infections, diet and sexual intercourse. The condition affects people in all walks of life.

The symptoms of IC are similar to other disorders of the urinary system. There is no definitive test to identify IC and therefore, doctors must exclude other potential conditions before considering a diagnosis of IC.

Bladder pain, frequent urination, and even painful sexual intercourse can have significant impact on the long-term quality of your life. If you have the symptoms of IC, consult your physician.

 

Signs and Symptoms:

The signs and symptoms of interstitial cystitis vary from person to person. In addition, the symptoms of each affected person may vary over time, periodically flaring in response to common triggers such as menstruation, seasonal allergies, stress and sexual activity.

Interstitial cystitis symptoms include:

  • A persistent, urgent need to urinate.
  • Frequent urination that occurs both during the day and during the night, yet you may pass only small volumes of urine each time.
  • People with severe interstitial cystitis may urinate as often as 60 times a day.
  • Pain in your pelvis (suprapubic) or between the vagina and anus in women or the scrotum and anus in men (perineal).
  • Pelvic pain during sexual intercourse. Men may also experience painful ejaculation.
  • Chronic pelvic pain.

More than 15 percent of people affected by interstitial cystitis experience only symptoms of pain, and at least 30 percent experience only frequent, urgent urination. Most affected people, however, experience both pain and frequent, urgent urination.

Although signs and symptoms of interstitial cystitis may resemble those of a chronic urinary tract infection, urine cultures are usually free of bacteria. A worsening of symptoms may occur if a person with interstitial cystitis gets a urinary tract infection.

 

Therapy: GAG Replenishment

IC patients have defects in the protective lining on the inner wall of the urinary bladder. This lining is made up of substances called GAG layer, which protect the bladder wall from toxic effects of urine and its contents. Damage causes leaks in the protective Glycosaminoglycan layer, which may then allow substances in urine to pass into the bladder wall and trigger IC symptoms.

 

Treatment Program:

  • It is recommended that BioCyst be instilled once a week for 4 to 6 weeks and then monthly thereafter as directed by the Physician.
  • BioCyst must be held in the bladder for minimum 20 to 30 minutes. Response will vary from patient to patient but optimum response usually takes 4 to 6 months and should be continued for at least one year before interrupting treatment.
  • One treatment is given every one or two weeks for four to eight treatments, depending on the patient's response to the medication and as directed by the Physician.
  • For some patients with severe IC, a more aggressive therapy is recommended. These patients should have instillations on a bi-weekly basis for 6 weeks. Instillations are then continued on a monthly basis for twelve months.

Supply:

  • BioCyst